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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDX1 All Species: 22.73
Human Site: S29 Identified Species: 45.45
UniProt: P52945 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52945 NP_000200.1 283 30771 S29 R G P A P E F S A S P P A C L
Chimpanzee Pan troglodytes A2T756 283 30712 S29 R G P A P E F S A G P P A C L
Rhesus Macaque Macaca mulatta XP_001096758 281 30575 S29 R G P A P E F S A S P P A C L
Dog Lupus familis XP_543155 532 56855 S279 R G P A P E F S A S P P A C L
Cat Felis silvestris
Mouse Mus musculus P52946 284 30981 S29 R G P V P E F S A N P P A C L
Rat Rattus norvegicus P52947 283 30812 S29 R G P V P E F S A N P P A C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519548 259 28495 H29 R C P A Q D F H P S P P A C L
Chicken Gallus gallus XP_001234636 231 26345 S29 R A Q D Y S P S P P A C L Y V
Frog Xenopus laevis P14837 271 31388 N29 R S Q G Q D Y N P S P P A C L
Zebra Danio Brachydanio rerio O42370 396 43083 N77 R P S A S Q G N S Q P E S I S
Tiger Blowfish Takifugu rubipres Q1KKS7 408 44369 A92 Q P G P P L S A S S P S P N S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999815 390 43430 P95 P M H S P T N P Q D L S R P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.2 49.6 N.A. 87.6 88.6 N.A. 64.3 63.2 57.9 26.7 26.9 N.A. N.A. N.A. 31.5
Protein Similarity: 100 99.2 98.5 50 N.A. 89.4 90.1 N.A. 71 70.6 66.7 36.6 36.7 N.A. N.A. N.A. 44.1
P-Site Identity: 100 93.3 100 100 N.A. 86.6 86.6 N.A. 66.6 13.3 46.6 20 20 N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 93.3 N.A. 73.3 20 66.6 46.6 40 N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 50 0 0 0 9 50 0 9 0 67 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 9 0 67 0 % C
% Asp: 0 0 0 9 0 17 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 50 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 9 9 0 0 9 0 0 9 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 9 0 9 0 75 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 17 0 17 0 0 0 9 0 % N
% Pro: 9 17 59 9 67 0 9 9 25 9 84 67 9 9 0 % P
% Gln: 9 0 17 0 17 9 0 0 9 9 0 0 0 0 0 % Q
% Arg: 84 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 9 9 9 9 9 9 59 17 50 0 17 9 0 17 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _